In the name of ALLAH, the most beneficient, the most merciful

Cell and Molecular Biology (ZOO505)

Multiple Choice Questions (MCQs)

Objective Questions

  1. In ________, transcription factors help polymerase in binding to promoter and also help in melting of DNA.

    1. translation termination
    2. replication initiation
    3. pre-initiation complex
    4. elongation of RNA
  2. ________ protein initiates the process of termination in transcription.

    1. polymerase
    2. Rho
    3. Rno
    4. primase
  3. The binding between the TFB-TATA and TFIIB is ________.

    1. asymmetric
    2. symentric
    3. linear
    4. regular
  4. In the formation of preinitiation complex, the strongest binding is found between ________.

    1. TBB and TATA
    2. TBP and TATA
    3. preinitiation complex
    4. TAF and TBF
  5. Xrn2 is a RNAase present in ________.

    1. animals
    2. humans
    3. yeast
    4. fungi
  6. ELL is a ________ in transcription process.

    1. initiation factor
    2. elongation factor
    3. termination factor
    4. helicase
  7. ________ binds with block A and block B of tRNA in the process of transcription.

    1. TFIIC
    2. TFIIIC
    3. TFIIB
    4. TFIIIB
  8. TFIIF is a transcription factor with ________ subunits.

    1. 0
    2. 1
    3. 2
    4. 3
  9. From mRNA, intronic sequences are removed by breaking ________ bonds.

    1. hydrogen
    2. ionic
    3. polar
    4. phosphodiester
  10. Series of three nucleotides is called ________.

    1. tRNA
    2. noncoding sequence
    3. coding sequence
    4. replica sequence
  11. Rat1 is an RNAase found in ________.

    1. algae
    2. fungi
    3. yeast
    4. animals
  12. Rho uses the energy derived from ________.

    1. polymerization
    2. ATP hydrolysis
    3. anabolism
    4. metabolism
  13. The terminator sequence in protein synthesis has ________ rich regions.

    1. AC
    2. AU
    3. GC
    4. AT
  14. In transcription, the process is samein both prokaryotes and eukaryotes but the ________ is different.

    1. steps
    2. machinery
    3. genetic makeup
    4. nucleotides
  15. Which of the following is an example of huge molecular machine?

    1. spliceosome
    2. polymerase
    3. RNAse
    4. DNAse
  16. The removal of introns by introns itself through specific conformation is called ________.

    1. Self - splicing
    2. Normal splicing
    3. Relatable splicing
    4. Intron removal
  17. ________ is recruited to polymerase by transcriptional activators.

    1. kinase
    2. helicase
    3. isomerase
    4. reductase
  18. snRNPs stands for ________.

    1. smaller nuclear ribo-RNPs
    2. smaller RNPs
    3. small nuclear proteins
    4. small nuclear ribonuclear proteins
  19. Early E complex is an arrangement of ________.

    1. DNA and RNA
    2. RNA and proteins
    3. DNA and proteins
    4. Proteins and proteins
  20. To terminate transcription, Rho must move over ________ to reach polymerase.

    1. elongating RNA
    2. DNA template
    3. helicase
    4. lagging strand
  21. TFIIF function as ________ in the ATPase driven process.

    1. inducer
    2. translocator
    3. terminator
    4. initiator
  22. Alternatively, the transcriptional regulatory proteins are also known as ________.

    1. enhancers
    2. activators
    3. regulators
    4. stabilizers
  23. The process of elongation starts when ________ skips the promoter sequence.

    1. polymerase
    2. gyrase
    3. helicase
    4. topoisomerase
  24. TFIIH are ________.

    1. kinases
    2. reductases
    3. oxidases
    4. phosphorylases
  25. Amino acids must attach to adapter molecules before peptide formation, it was proposed in ________.

    1. 1956
    2. 1955
    3. 1945
    4. 1845
  26. During the process of transcription TFIIS performs the function of ________.

    1. polymerisation
    2. proofreading
    3. uncoiling
    4. nick binding
  27. During the process of intron removal, ________ is formed.

    1. splice site
    2. nick
    3. lariat
    4. ester
  28. The removal of intron is done by linear and lariat patterns.

    1. true statement
    2. false statement
    3. both are wrong
    4. only linear patterns are seen
  29. In eukaryotes, introns are ________.

    1. noncoding sequence
    2. coding sequence
    3. replica sequence
    4. block of genes
  30. TFIIIC is responsible for recruiting ________ in the process of transcription.

    1. TFIIIB
    2. TFIIB
    3. TFIIB
    4. TFAK
  31. Hairpin stem loop is formed in the process of ________.

    1. transcription
    2. replication
    3. translation
    4. respiration
  32. In transcription, the formation of preinitiation complex is followed by ________.

    1. termination
    2. elongation
    3. initiation
    4. polymerization
  33. What is the meaning of a berrant splicing?

    1. correct splicing
    2. wrong splicing
    3. normal splicing
    4. accurate splicing