In the name of ALLAH, the most beneficient, the most merciful

Cell and Molecular Biology (ZOO505)

Multiple Choice Questions (MCQs)

Objective Questions

  1. To terminate transcription, Rho must move over ________ to reach polymerase.

    1. elongating RNA
    2. DNA template
    3. helicase
    4. lagging strand
  2. The process of elongation starts when ________ skips the promoter sequence.

    1. polymerase
    2. gyrase
    3. helicase
    4. topoisomerase
  3. In ________, transcription factors help polymerase in binding to promoter and also help in melting of DNA.

    1. translation termination
    2. replication initiation
    3. pre-initiation complex
    4. elongation of RNA
  4. ________ binds with block A and block B of tRNA in the process of transcription.

    1. TFIIC
    2. TFIIIC
    3. TFIIB
    4. TFIIIB
  5. What is the meaning of a berrant splicing?

    1. correct splicing
    2. wrong splicing
    3. normal splicing
    4. accurate splicing
  6. Amino acids must attach to adapter molecules before peptide formation, it was proposed in ________.

    1. 1956
    2. 1955
    3. 1945
    4. 1845
  7. snRNPs stands for ________.

    1. smaller nuclear ribo-RNPs
    2. smaller RNPs
    3. small nuclear proteins
    4. small nuclear ribonuclear proteins
  8. ________ protein initiates the process of termination in transcription.

    1. polymerase
    2. Rho
    3. Rno
    4. primase
  9. Early E complex is an arrangement of ________.

    1. DNA and RNA
    2. RNA and proteins
    3. DNA and proteins
    4. Proteins and proteins
  10. TFIIIC is responsible for recruiting ________ in the process of transcription.

    1. TFIIIB
    2. TFIIB
    3. TFIIB
    4. TFAK
  11. Xrn2 is a RNAase present in ________.

    1. animals
    2. humans
    3. yeast
    4. fungi
  12. Hairpin stem loop is formed in the process of ________.

    1. transcription
    2. replication
    3. translation
    4. respiration
  13. TFIIF function as ________ in the ATPase driven process.

    1. inducer
    2. translocator
    3. terminator
    4. initiator
  14. Rat1 is an RNAase found in ________.

    1. algae
    2. fungi
    3. yeast
    4. animals
  15. During the process of intron removal, ________ is formed.

    1. splice site
    2. nick
    3. lariat
    4. ester
  16. In transcription, the formation of preinitiation complex is followed by ________.

    1. termination
    2. elongation
    3. initiation
    4. polymerization
  17. Rho uses the energy derived from ________.

    1. polymerization
    2. ATP hydrolysis
    3. anabolism
    4. metabolism
  18. Which of the following is an example of huge molecular machine?

    1. spliceosome
    2. polymerase
    3. RNAse
    4. DNAse
  19. During the process of transcription TFIIS performs the function of ________.

    1. polymerisation
    2. proofreading
    3. uncoiling
    4. nick binding
  20. In the formation of preinitiation complex, the strongest binding is found between ________.

    1. TBB and TATA
    2. TBP and TATA
    3. preinitiation complex
    4. TAF and TBF
  21. ________ is recruited to polymerase by transcriptional activators.

    1. kinase
    2. helicase
    3. isomerase
    4. reductase
  22. The terminator sequence in protein synthesis has ________ rich regions.

    1. AC
    2. AU
    3. GC
    4. AT
  23. ELL is a ________ in transcription process.

    1. initiation factor
    2. elongation factor
    3. termination factor
    4. helicase
  24. The removal of introns by introns itself through specific conformation is called ________.

    1. Self - splicing
    2. Normal splicing
    3. Relatable splicing
    4. Intron removal
  25. The binding between the TFB-TATA and TFIIB is ________.

    1. asymmetric
    2. symentric
    3. linear
    4. regular
  26. In transcription, the process is samein both prokaryotes and eukaryotes but the ________ is different.

    1. steps
    2. machinery
    3. genetic makeup
    4. nucleotides
  27. In eukaryotes, introns are ________.

    1. noncoding sequence
    2. coding sequence
    3. replica sequence
    4. block of genes
  28. TFIIH are ________.

    1. kinases
    2. reductases
    3. oxidases
    4. phosphorylases
  29. TFIIF is a transcription factor with ________ subunits.

    1. 0
    2. 1
    3. 2
    4. 3
  30. From mRNA, intronic sequences are removed by breaking ________ bonds.

    1. hydrogen
    2. ionic
    3. polar
    4. phosphodiester
  31. Alternatively, the transcriptional regulatory proteins are also known as ________.

    1. enhancers
    2. activators
    3. regulators
    4. stabilizers
  32. The removal of intron is done by linear and lariat patterns.

    1. true statement
    2. false statement
    3. both are wrong
    4. only linear patterns are seen
  33. Series of three nucleotides is called ________.

    1. tRNA
    2. noncoding sequence
    3. coding sequence
    4. replica sequence