In the name of ALLAH, the most beneficient, the most merciful

Cell and Molecular Biology (ZOO505)

Multiple Choice Questions (MCQs)

Objective Questions

  1. In ________, transcription factors help polymerase in binding to promoter and also help in melting of DNA.

    1. translation termination
    2. replication initiation
    3. pre-initiation complex
    4. elongation of RNA
  2. Xrn2 is a RNAase present in ________.

    1. animals
    2. humans
    3. yeast
    4. fungi
  3. During the process of transcription TFIIS performs the function of ________.

    1. polymerisation
    2. proofreading
    3. uncoiling
    4. nick binding
  4. ELL is a ________ in transcription process.

    1. initiation factor
    2. elongation factor
    3. termination factor
    4. helicase
  5. The removal of introns by introns itself through specific conformation is called ________.

    1. Self - splicing
    2. Normal splicing
    3. Relatable splicing
    4. Intron removal
  6. ________ protein initiates the process of termination in transcription.

    1. polymerase
    2. Rho
    3. Rno
    4. primase
  7. Early E complex is an arrangement of ________.

    1. DNA and RNA
    2. RNA and proteins
    3. DNA and proteins
    4. Proteins and proteins
  8. TFIIIC is responsible for recruiting ________ in the process of transcription.

    1. TFIIIB
    2. TFIIB
    3. TFIIB
    4. TFAK
  9. TFIIF is a transcription factor with ________ subunits.

    1. 0
    2. 1
    3. 2
    4. 3
  10. The removal of intron is done by linear and lariat patterns.

    1. true statement
    2. false statement
    3. both are wrong
    4. only linear patterns are seen
  11. Alternatively, the transcriptional regulatory proteins are also known as ________.

    1. enhancers
    2. activators
    3. regulators
    4. stabilizers
  12. In the formation of preinitiation complex, the strongest binding is found between ________.

    1. TBB and TATA
    2. TBP and TATA
    3. preinitiation complex
    4. TAF and TBF
  13. What is the meaning of a berrant splicing?

    1. correct splicing
    2. wrong splicing
    3. normal splicing
    4. accurate splicing
  14. To terminate transcription, Rho must move over ________ to reach polymerase.

    1. elongating RNA
    2. DNA template
    3. helicase
    4. lagging strand
  15. snRNPs stands for ________.

    1. smaller nuclear ribo-RNPs
    2. smaller RNPs
    3. small nuclear proteins
    4. small nuclear ribonuclear proteins
  16. During the process of intron removal, ________ is formed.

    1. splice site
    2. nick
    3. lariat
    4. ester
  17. Rat1 is an RNAase found in ________.

    1. algae
    2. fungi
    3. yeast
    4. animals
  18. Series of three nucleotides is called ________.

    1. tRNA
    2. noncoding sequence
    3. coding sequence
    4. replica sequence
  19. TFIIF function as ________ in the ATPase driven process.

    1. inducer
    2. translocator
    3. terminator
    4. initiator
  20. Amino acids must attach to adapter molecules before peptide formation, it was proposed in ________.

    1. 1956
    2. 1955
    3. 1945
    4. 1845
  21. Hairpin stem loop is formed in the process of ________.

    1. transcription
    2. replication
    3. translation
    4. respiration
  22. The process of elongation starts when ________ skips the promoter sequence.

    1. polymerase
    2. gyrase
    3. helicase
    4. topoisomerase
  23. In transcription, the process is samein both prokaryotes and eukaryotes but the ________ is different.

    1. steps
    2. machinery
    3. genetic makeup
    4. nucleotides
  24. In eukaryotes, introns are ________.

    1. noncoding sequence
    2. coding sequence
    3. replica sequence
    4. block of genes
  25. ________ is recruited to polymerase by transcriptional activators.

    1. kinase
    2. helicase
    3. isomerase
    4. reductase
  26. TFIIH are ________.

    1. kinases
    2. reductases
    3. oxidases
    4. phosphorylases
  27. Which of the following is an example of huge molecular machine?

    1. spliceosome
    2. polymerase
    3. RNAse
    4. DNAse
  28. ________ binds with block A and block B of tRNA in the process of transcription.

    1. TFIIC
    2. TFIIIC
    3. TFIIB
    4. TFIIIB
  29. The binding between the TFB-TATA and TFIIB is ________.

    1. asymmetric
    2. symentric
    3. linear
    4. regular
  30. Rho uses the energy derived from ________.

    1. polymerization
    2. ATP hydrolysis
    3. anabolism
    4. metabolism
  31. The terminator sequence in protein synthesis has ________ rich regions.

    1. AC
    2. AU
    3. GC
    4. AT
  32. From mRNA, intronic sequences are removed by breaking ________ bonds.

    1. hydrogen
    2. ionic
    3. polar
    4. phosphodiester
  33. In transcription, the formation of preinitiation complex is followed by ________.

    1. termination
    2. elongation
    3. initiation
    4. polymerization