Multiple Choice Questions (MCQs)
histones are ________ charged
A DNA segment contains 100 Adenine and 100 cytosines, how many nucleotides are present in the segment?
higher GC base pairs increases Tm, because, with three hydrogen bonds, require ________ heat energy to dissociate than AT base pairs.
Disruption of DNA can occur in the laboratory with alteration in
In living cells, nucleotides and their derivatives can serve as:
The Tm of DNA is influenced by
Which one of the following is true of the pentoses found in nucleic acids?
Find the correct statement about phosphodiester linkage between adjacent nucleotides in nucleic acids
These ________ bonds, plus the van der Waals and hydrophobic interactions between the adjacent stacked bases, stabilize the structure of the double helix.
In a double-stranded nucleic acid, cytosine typically base-pairs with:
A short length of DNA molecule has 80 thymine and 80 guanine bases. The total number of nucleotide in the DNA fragment is
The DNA wrapped around the nucleosome core is continuous and joins one nucleosome core to the next -the linker DNA this 50 bp DNA is complexed with the fifth type of histone. ________
DNA model was presented by Watson and Crick in ________.
The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA:
DNA that is not copied during the synthesis of mRNA is also called as
Which of the following is a palindromic sequence?
RNA duplexes are ________ stable than DNA duplexes.
The ________ strand is called Template strand while
Nucleotides are composed of
Z-DNA have a
The "energy carrier" ATP is an example of a(n):
Chromatin is composed of
Around structural core of the nucleosome, a segment of the DNA double helix is wound nearly twice-approximately ________.
Certain anticancer drugs, exert their cytotoxic effect by intercalating into the ________ groove of the DNA double helix, thus interfering with RNA and DNA synthesis
When DNA is heated, the temperature at which ________ of the helical structure is lost is defined as the melting temperature.
According to Chargaff's Rules which one is not correct
A phosphodiester bond is present in
Compounds that generate nitrous acid (such as nitrites, nitrates, and nitrosamines) change DNA molecules by:
Adenosine 3'-phosphate-5'-phosphosulfate is the ________ donor.
Nucleotides also serve as carriers of activated intermediates in the synthesis of ________.
Purine base found in RNA is
Under appropriate conditions DNA will form a hybrid with a complementary ________.
The sugar molecule present in nucleotide is
Nucleoside contains
The difference between thymine and uracil is:
The DNA oligonucleotide abbreviated pATCGAC:
Nucleic acids are a polymer of nucleotide monomeric units. Each nucleotide consists of
There are ________ classes of histones
DNA replication is
S-adenosylmethionine is a ________ group donor.
Which one is example of coenzymes
When linked to vitamins nucleotides are structural components of several essential coenzymes, for example,
Nucleosomes can be packed more tightly to form a polynucleosome also called a nucleofilament or a ________nm fiber.
Any regular, stable structure taken up by some or all of the nucleotides in a nucleic acid can be referred to as
The complex folding of large chromosomes within eukaryotic chromatin and bacterial nucleoids is generally considered ________.
single-stranded DNA has a ________ relative absorbance at 260nm wavelength than does double-stranded DNA.
Eukaryotic DNA is associated with tightly bound basic ________, called histones.
ATP is a
Separation of the two strands of the double helix when ________ bonds between the paired bases are disrupted.
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