Bioinformatics II (BIF501)

1. What is meant by ADME in pharmacokinetics?

   1. Affinity, dosage, marketing, efficacy
   2. Absorption, distribution, metabolism, excretion
   3. Agonism, dependence, mobility, efficiency
   4. Antagonism, deficiency, mean, efflux

2. How many reads are required to map at 1 RPKM with a transcript of 2Kb length from a total of 40 Million Mapped reads?

   1. 60
   2. 70
   3. 80
   4. 90

3. ________ breaks cell membrane and nuclear envelope causing cells to burst open and release DNA.

   1. Lysis Solution
   2. Nuclease
   3. Protease
   4. Restriction enzymes

4. Neural network is an interconnectrd web of ________.

   1. Networks
   2. Neuron
   3. Nodes
   4. Edges

5. ________ replicate a small amount of DNA to create a larger sample for analysis.

   1. Polymerase chain Reaction (PCR)
   2. Gel Electrophoresis
   3. Flow cytometry
   4. Mass Spectrometry

6. A forensic scientist will need at least ________ pieces of DNA to be compared.

   1. Two
   2. Three
   3. Four
   4. Five

7. ________ is encrypted sets of numbers that reflect a person's DNA makeup.

   1. DNA fingerprints
   2. DNA profile
   3. cDNA
   4. DNA sequence reads

8. CAT is repeated continuously ________ times in a row.

   1. 12 to 14
   2. 15 to 17
   3. 18 to 20
   4. 21 to 23

9. An association rule has ________ parts.

   1. Two
   2. Three
   3. Four
   4. Five

10. Polymerase Chain Reaction is a

    1. DNA degradation technique
    2. DNA amplification technique
    3. DNA sequencing technique
    4. DNA sampling technique

11. How genes affect persons response to drug is study in ________.

    1. Drug discovery
    2. Pharmacogenetics
    3. Pharmacogenomics
    4. Pharmacophore modeling

12. In 3D-1D Bowie Algorithm there are ________ distinct states (1D profiles) for 20 amino acid.

    1. 120
    2. 240
    3. 360
    4. 480

13. If you want to create a fingerprint, you might look at ________ different STRs at different places to create a profile.

    1. 10
    2. 20
    3. 30
    4. 40

14. Machine learning is used when

    1. Human expertise exists
    2. Humans can explain their expertise like speech recognition
    3. Problem solution changes in time
    4. Problem solution is fixed

15. Lysis Solution removes the ________ proteins from the DNA.

    1. Polymerase
    2. Histone
    3. Helicase
    4. Nuclease

16. The length of DNA in a cell is ________.

    1. One meter
    2. Two meters
    3. Three meters
    4. Four meters

17. How much percentage of DNA sequence is unique enough to differentiate two humans.

    1. 0.001
    2. 0.01
    3. 0.1
    4. 1.0

18. Protein core is ________.

    1. Hydrophobic
    2. Hydrophilic
    3. Amphipathic
    4. Non-Amphipathic

19. iTasser input is ________.

    1. Sequence of DNA
    2. Sequence of RNA
    3. Sequence of Amino Acid
    4. Genome Sequence

20. Which tool is used for threading ________.

    1. Modeller
    2. LOMETS
    3. ECEPPAK
    4. iTasser

21. In homology modeling fewer than ________ of the predicted first hits are true remoted homologues.

    1. 10%
    2. 20%
    3. 30%
    4. 40%

22. Mass spectrometry is used to sequence ________ length proteins.

    1. Smaller
    2. Larger
    3. Medium
    4. All of the given

23. In PCR the DNA sample is heated to ________ separate the thread.

    1. 90 degrees
    2. 91 degrees
    3. 92 degrees
    4. 93 degrees

24. All human share ________ percentage of their DNA sequence.

    1. 50.8
    2. 70.3
    3. 85.9
    4. 99.9

25. ________ is a process of organizing objects into groups whose members are similar in some way.

    1. Classification
    2. Clustering
    3. Grouping
    4. Stacking

Select a course code for Objective Questions:

ACC311 ACC501 BIF101 BIF401 BIF501 BIO101 BIO201 BIO202 BIO203 BIO204 BIO301 BIO302 BIO303 BIO401 BIO503 BNK603 BT101 BT201 BT301 BT302 BT401 BT402 BT403 BT404 BT405 BT406 BT501 BT504 BT505 BT604 CHE201 CHE301 CS001 CS101 CS201 CS202 CS204 CS301 CS302 CS304 CS311 CS401 CS402 CS403 CS408 CS501 CS502 CS504 CS506 CS508 CS601 CS602 CS604 CS605 CS607 CS609 CS610 CS614 CS707 CS710 ECO401 ECO402 ECO403 ECO404 EDU302 EDU401 EDU402 EDU501 EDU601 ENG101 ENG201 ENG301 ENG501 FIN611 FIN624 FIN625 ISL201 IT430 MCM101 MCM301 MGMT623 MGT101 MGT211 MGT301 MGT401 MGT402 MGT501 MGT502 MGT503 MGT510 MGT601 MGT603 MKT501 MKT610 MKT630 MTH101 MTH202 MTH302 MTH501 MTH601 MTH634 PAK301 PHY101 PHY301 PSY101 PSY403 PSY502 PSY512 SOC101 SOC301 SOC401 STA301 STA630 STA641 ZOO102 ZOO401 ZOO501 ZOO502 ZOO503 ZOO504 ZOO505 ZOO506 ZOO510 ZOO630

Select a course code for Subjective Questions:

ACC311 CS001 CS101 CS201 CS301 CS607 CS701 CS702 CS703 CS704 CS707 CS708 CS710 CS711 CS718 CS721 CS724 ECO401 ECO403 ENG101 ENG301 MGT703 MTH501 STA301