Multiple Choice Questions (MCQs)
X-Ray data need a minimum of ________ resolution.
In Bottom up proteomics, Enzyme ________ is used to cleave the proteins.
Messenger RNA is only ________ of RNA content in the cell.
What are 2 things required in order to successfully use the dynamic programming technique?
Bioinformatics is the interdisciplinary relative new development of ________.
The correct order of progressive alignment steps for multiple sequence alignment is ________ .
Dot plot of repeating elements would be small crosses on plot.
GenBank and SWISSPORT are example of
Sum of stabilizing and destabilizing energies can help determine the ________.
Which of the following is untrue anout the modification of PAM matrices?
To determine the number of each type of interaction within a protein, we need to find its inter atomic distances.
The major element of secondary structure in myoglobin and hemoglobin is:
________ compares protein sequence against protein databases.
Beta Sheets are secondary structure that can be formed as a result of ________.
The secondary structure of a protein consists of all but one of the following, which is odd one out?
The ________ tool compares nucleotide sequence against DNA database.
C-Alpha atoms are traced to recreate the ________ protein structure.
Choose the incorrect statement out of the following?
BLASTX uses protein sequences as queries to search against a protein sequence database.
Zuker's Algorithm involves energy ________.
Which of these bonds is not involved in forming the secondary structure of a protein?
The identification of drugs through genomic study is known as
Addition or removal of amino acids from protein sequences or nucleotides from DNA or RNA sequences is known as?
What is the source of protein structures in SCOP and CATH?
Beeta-pleated sheets are the examples of ________.
The Alignment method suitable for finding out conserved patterns in DNA or Protein sequences is
Which of the following is the character based phylogenetic tree construction methods?
Which one of the following issues are addressed by using computational methods, data processing techniques and algorithms?
RNA is found in the nucleolus of the cell and DNA is found in
Black analysis methods use substitution matrices such as the PAM and BLOSUM matrices to score matches.
In multiple sequence alignment (MSA), we have ________ .
GeneBank and UniPort have
The procedure of aligning two sequences by searching of patterns that is in the same order in the sequences?
The basic idea of thermodynamic stability is to maximize bonding in order to minimize the free energy.
Visualization methods are very important in viewing molecular properties on molecules. Of particular note is the rendering of molecular surfaces according to their various properties (that can be expressed numerically).
Analyzing or comparing entire genome of species known as,
In a similar way to structure prediction methods can be evaluated using RMSD to measure the similarity between two molecular complexes.
X-ray diffraction data helps measure ________.
The first RNA processing event is
How many types of secondary structures can be formed possibly by folding of RNA?
There are 64 codons in the genetic dictionary as:
Which one of the following types of bond is principally responsible for holding the α-helix shape of a protein secondary structure?
rRNA is synthesized by:
The interactions which holds and stabilizes the sub-units in 4' structure of proteins are:
Which of the following doesn't describe PAM matrices?
Laboratory work using computers and computer-generated models generally offline is referred as:
Nussinov-Jacobson (NJ) Algorithm is a dynamic Programming (DP) strategy to predict ________.
mRNA directs the building of proteins through a sequence of
If two atoms are participating in a covalent bond, their distance will be equal to?
74- Scoring Matrices contains,
A Protein Data Bank (PDB) data file for a protein structure contains only x and y coordinates of atoms.
In the alpha helix the hydrogen bond:
Progressive alignment methods use the dynamic programming method to build a MSA starting with the most related sequences and then progressively adding less related sequences or groups of sequences to the initial alignment?
X-Ray Crystallography data shows that hydrogen atoms of N-Term may come together with Oxygen atoms of C-term amino acid at ________ position.
Which of the following is not a benefit or a factual of FASTA over BLAST?
CLUSTALW is a more recent version of CLUSTAL with the W standing for ________.
The scoring of gaps in a MSA (Multiple Sequence Alignment) has to be performed in a different manner from scoring gaps in a pair-wise alignment?
Dynamic Programming uses a "________" to deal with matches, mismatches and gaps.
Messenger RNA is
In multiple sequence alignment ________ .
In dynamic programming we can do multiple sequence alignment upto ________
All are nucleotide sequence database, except
The BLAST program was developed in ________ .
________ are the units of proteins.
For which one of the following activities, bioinformatics is used in modern biological sciences?
Unfolding of a protein can be termed as ________.
Who discovered diffraction pattern for DNA?
Name any two frequently used scoring matrices
The putative ORF can be translated into a protein sequence, which is then used to search against a protein database.
The greater the number of bonds between the amino acids, the ________ stable a protein becomes.
Which of the following is untrue about the Unweighted Pair Group Method Using Arithmetic Average?
Which algorithm is used by global alignment?
Which one of the following is not a "Sequence Alignment Tool"?
In GenBank, specific gene can be searched by using?
Bioinformatics can deliver:
Your lab partner is using BLAST, and his best E-value is 3. This means that
Single letter code of Tyrosine is ________.
Balls and sticks are solid spheres and rods, representing atoms and bond, respectively.
Translation is the process in which
DNA makes RNA and RNA makes protein, this process is termed as
Which of the following doesn't describe local alignment?
Elongation of transcription and RNA processing are all interconnected?
Alpha Helices are formed by hydrogen bonding between ________ and ________ atoms in the protein backbone?
Alpha helices and beta sheets are formed because of ________.
FASTA format start with ________ symbol.
Which of the following methods are broad class of computational algorithms that rely on repeated random sampling to obtain numerical results.
An alpha helix is formed by hydrogen bonding between the hydrogen of an amine group and the backbone carbonyl group how many amino acids upstream of it?
RNA is the genetic material in
Which of the following is not protein fragmentation technique.
Block analysis methods use substitution matrices such as the PAM and BLOSUM matrices to score matches.
The study of full complement of proteins expressed by a genome is called
Mfold gives out (output) several structures along with their ________.
How many proteins does the human body produce?
Which of the following statements about amino acids is correct?
In Corey-Paulin-Koltun Diagram, each atom is represented by ________.
Amino acids are mostly synthesized from
Which one of the following methods can be used for statistical evaluation of data?
Which of the following is the correct order of organization of genetic material from largest to smallest?
The peptide bond in protein is:
Which is the default scoring matrix used in BLAST?
The ________ E-Value, the more significant the hit.
Amino acids are joined together to form polypeptides. Each amino acid is attached to another by a peptide bond. What functional group is created when amino acids are joined together?
Ribbon diagram use cylinders or spiral ribbons to represent alpha-helices and broad, flat arrows to represent beeta-strands.
The Phi and Psi values of a Beta-strand composed of all D-amino acids will mainly occupy which quadrant in the Ramachandran plot?
Which one of the following are Archaea?
All of the following are protein sequence databases except ________.
Which of the following is not a benefit of BLAST?
Which of the following is not a variant of BLAST?
All of the following are protein sequence database, except ________.
Which one of the following is not a tool for protein visualization?
GenBank database is maintained by ________.
Amino acids are chained together by ________.
Which of the following is not an ionization techniques in proteins?
Which of the following is the smallest of the RNAs?
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