Handouts | Lectures | Contents | Books
Genetics Definition, Types of Genetics ,Genetics Terminologies ,Mendel s’ law of Dominance Monohybrid Cross and Dihybrid Cross , Mendel s’ law of Segregations , Mendel s' law of Independent Assortment Modern Genetics Concepts Importance of Genetics Heredity Variation Genetic and Acquired Variation Types of Variation Source of variation Heredity and Variation in Mendel s’ work Mendelian and Non-Mendelian Inheritance Conclusions of Mendelian Inheritance Exceptions to Mendelian Inheritance Incomplete Dominance Co-dominance Polygenic traits Epistasis Pleiotropy Environmental Effects What are Chromosomes Cell, Nucleus and Chromosome Chromosome Numbers in Different Species Chromosomes in Prokaryotes and Eukaryotes Salient features of Chromosomes Size of Chromosomes Types of Chromosomes Centromere Functions Telomere Functions Euchromatin and Heterochromatin Staining and Banding Chromosomes Nucleosomes Chromatin and Chromosomes High Order Chromatin Folding Kinetochore Karyotyping Prokaryotic Chromosomes Sex Chromosomes and Sex determination Salient features of DNA Nucleotides Conformations of DNA Chargaff Rule of Base Ratio Giant Chromosomes Lampbrush chromosome Cell Division Cell Cycle Mitosis Unreplicated and Replicated Chromosomes Interphase Prophase of Mitosis Metaphase of Mitosis Anaphase of Mitosis Telophase of Mitosis Cytokinesis Mitotic Spindles Somatic cells and Gametes Homologous Chromosomes Meiosis Stages of Meiosis Prophase I of Meiosis Metaphase I of Meiosis Anaphase I of Meiosis Telophase I of Meiosis Prophase II of Meiosis Metaphase II of Meiosis Anaphase II of Meiosis Telophase II of Meiosis Mitosis and Meiosis Summary - Mitosis and Meiosis Chromosomal Theory of Inheritance Experiments of T H. Morgan Effect of Linkage on Inheritance Linkage Mapping Linkage map of Drosophila Chromosome Chromosomal Basis of Sex Determination Sex Determination in Other Organisms Inheritance of Sex linked genes Genetic Mapping in Humans Concept of Multiple Alleles Multiple Alleles - our blood group Blood groups and Transfusions Multiple alleles effect in Drosophila Correlation of Alleles and Genotypes Linkage and Cross over Chromosome Mapping Genetic and Physical Map Mapping genes In human Pedigrees Polygenic Inheritance Examples of Polygenic inheritance What is Epistasis Types of Epistasis Types of Epistasis-Dominant Example of Epistasis-Labrador Retrievers What is Epigenetics Epigenetic Modifications Epigenetics regulated Phenomena Therapies Targeting Epigenetics Environmental Factors and Epigenetics Epigenetics- Conclusions Penetrance and Expressivity Penetrance and Expressivity- Example Chromosomal Aberrations Karyotyping- international description Defining Chromosome Location Common Numerical Abnormalities Structural Abnormalities Translocations Non-disjunction Trisomy Monosomy Polyploidy Alloploidy Polyploidy and Aneuploidy Chromosomal Deletions Chromosomal Insertions Chromosomal Inversions Ring Chromosome What is Mutation Types of Mutation Somatic and Germline Mutation Forward, Reverse and Neutral Mutation Loss of function, Gain of function Spontaneous and Induced Mutation Suppressor Mutation Point Mutations Silent Mutation Missense Mutation Nonsense Mutation Additions Mutation Inversion Mutation Deletions Mutation How Mutations alter Gene Function Mutation Nomenclature Salient feature of Mutation Nomenclature Mutation at DNA, RNA and Protein level Mutation in Intronic Sequence Specific changes in Sequence Mutations-Summary What are Genetic Disorders Inheritance Patterns of Genetic Disorders Autosomal Recessive Inheritance Characteristics of Autosomal Recessive Inheritance Autosomal Dominant Inheritance Variation in Phenotype of A.D. inheritance Dominance and Recessiveness X-linked recessive inheritance X-linked dominant inheritance Maternal inheritance of mt DNA Multifactorial inheritance Frequency of genetic disorders Diagnostic tests for genetic disorders Genetic counseling Complications to basic inheritance pattern Drawing pedigree Pedigree analysis What is polymorphism Types of polymorphism Restriction fragment length polymorphism VNTR Short tandem repeat polymorphism RAPD and AFLP Distribution of SNPs, Screening and importance of SNPs . Practicals: Safety Protocols in a Genetics Lab Sources and Recovery of DNA Methods of DNA extraction and purification Methods of RNA purification from blood Affinity purification of total RNA Chromosome staining Banding of chromosomes (C, Q, R, T) Polymerase chain reaction (PCR) Types of polymerase chain reaction Southern blotting Western blotting Northern blotting Genetic problem-I Genetic problem-II Genetic problem-III Genetic problem-IV